| Department of Defense · DOD | USD 173,146,415,035 | 42,447 |
| Department of Energy · DOE | USD 83,102,745,231 | 466 |
| Department of Veterans Affairs · VA | USD 74,201,685,396 | 8,570 |
| Department of Homeland Security · DHS | USD 61,356,841,671 | 4,438 |
| National Aeronautics and Space Administration · NASA | USD 47,733,596,702 | 1,261 |
| Department of Health and Human Services · HHS | USD 10,882,851,742 | 3,491 |
| General Services Administration · GSA | USD 10,140,131,146 | 2,437 |
| Department of Transportation · DOT | USD 9,150,448,502 | 2,355 |
| Department of Agriculture · USDA | USD 8,292,381,851 | 4,898 |
| Department of State · DOS | USD 7,632,369,917 | 1,382 |
| Department of Justice · DOJ | USD 5,816,294,791 | 3,176 |
| Department of the Interior · DOI | USD 5,442,839,571 | 2,391 |
| Department of the Treasury · TREAS | USD 4,949,404,922 | 1,425 |
| Department of Commerce · DOC | USD 2,429,005,293 | 1,071 |
| Department of Education · ED | USD 1,856,166,231 | 152 |
| Department of Labor · DOL | USD 1,829,231,635 | 259 |
| Social Security Administration · SSA | USD 1,235,480,270 | 352 |
| Environmental Protection Agency · EPA | USD 774,531,014 | 449 |
| Department of Housing and Urban Development · HUD | USD 440,925,400 | 124 |
| Securities and Exchange Commission · SEC | USD 192,319,604 | 96 |
| National Archives and Records Administration · NARA | USD 172,084,127 | 52 |
| Peace Corps · PC | USD 136,138,385 | 18 |
| Federal Trade Commission · FTC | USD 116,337,622 | 33 |
| National Science Foundation · NSF | USD 105,963,765 | 75 |
| Agency for International Development · USAID | USD 103,256,917 | 14 |
| U.S. Agency for Global Media · USAGM | USD 64,452,941 | 70 |
| Government Accountability Office · GAO | USD 58,841,116 | 54 |
| Executive Office of the President · EOP | USD 52,430,045 | 40 |
| Pension Benefit Guaranty Corporation · PBGC | USD 51,340,748 | 27 |
| Corporation for National and Community Service · CNCS | USD 48,773,737 | 17 |
| District of Columbia Courts · DC COURTS | USD 48,540,065 | 51 |
| Consumer Financial Protection Bureau · CFPB | USD 47,374,210 | 21 |
| U.S. International Development Finance Corporation · DFC | USD 46,639,988 | 63 |
| Federal Communications Commission · FCC | USD 44,835,523 | 36 |
| Nuclear Regulatory Commission · NRC | USD 44,785,482 | 50 |
| Commodity Futures Trading Commission · CFTC | USD 38,121,390 | 17 |
| Office of Personnel Management · OPM | USD 34,359,796 | 16 |
| Court Services and Offender Supervision Agency · CSOSA | USD 31,411,590 | 27 |
| Equal Employment Opportunity Commission · EEOC | USD 31,398,726 | 40 |
| Millennium Challenge Corporation · MCC | USD 24,747,854 | 22 |
| National Labor Relations Board · NLRB | USD 24,120,401 | 25 |
| Federal Election Commission · FEC | USD 19,165,341 | 11 |
| Export-Import Bank of the United States · EXIM | USD 17,562,965 | 21 |
| National Transportation Safety Board · NTSB | USD 17,336,421 | 18 |
| Consumer Product Safety Commission · CPSC | USD 14,243,426 | 18 |
| Council of the Inspectors General on Integrity and Efficiency · CIGIE | USD 10,771,846 | 4 |
| Railroad Retirement Board · RRB | USD 10,549,045 | 10 |
| Institute of Museum and Library Services · IMLS | USD 9,874,485 | 15 |
| United States Trade and Development Agency · USTDA | USD 8,440,493 | 13 |
| National Endowment for the Arts · NEA | USD 5,678,779 | 4 |
| Federal Labor Relations Authority · FLRA | USD 3,190,435 | 2 |
| Selective Service System · SSS | USD 3,144,936 | 7 |
| Small Business Administration · SBA | USD 2,358,851 | 1 |
| Federal Maritime Commission · FMC | USD 1,786,332 | 4 |
| Merit Systems Protection Board · MSPB | USD 1,641,320 | 4 |
| Defense Nuclear Facilities Safety Board · DNFSB | USD 867,982 | 1 |
| American Battle Monuments Commission · ABMC | USD 861,248 | 1 |
| United States Chemical Safety Board · CSB | USD 843,998 | 2 |
| Committee for Purchase from People Who Are Blind or Severely Disabled · ABILITYONE | USD 375,448 | 1 |
| Federal Mediation and Conciliation Service · FMCS | USD 348,804 | 1 |
| National Endowment for the Humanities · NEH | USD 290,000 | 1 |
| International Trade Commission · USITC | USD 256,000 | 1 |